2. Signaling Pathways
  3. Immunology/Inflammation
  4. Interleukin Related
  5. IL-33 Isoform

IL-33

 

IL-33 Related Products (1):

Cat. No. Product Name Effect Purity
  • HY-P99444
    Astegolimab
    		Inhibitor 98.96%
    Astegolimab (MSTT 1041A; RG 6149) is a human IgG2 monoclonal antibody. Astegolimab blocks IL-33 signaling by targeting the IL-33 receptor ST2. Astegolimab reduces p53 expression, mitigates IL33-upregulated SASP factors such as IL1α, IL6 and MCP1. Astegolimab mitigates IL33-increased p-p65/p65 ratio. Astegolimab blocks CM-induced neutrophil extracellular trap (NET) formation. Astegolimab is used in chronic obstructive pulmonary disease (COPD) and myocardial research.